Tinnitus Miracle Book: 2016

Tuesday, March 29, 2016

The Zen of Tinnitus Acceptance

In the 1980s I absolutely loved punk rock. I lived in Greensboro, N.C. and struggling punker bands traveling from Atlanta to D.C. for weekend gigs would unload their equipment-filled vans into tiny bars for mid-week performances to pay for gas money for the trip. I would move toward the stage to listen to the raging of tatted, bare-chested men, roaring like aircraft engines, their words almost impossible to decipher. You didn’t need to. You didn’t listen to this music. You felt it. Now in my late ‘60s guess what I get? Can you say “tinnitus”? When it first showed up a decade or so ago I began wearing earplugs, closing doors quietly, and avoiding loud noises in the hopes that at least I could prevent further damage and perhaps turn down the volume a bit. It didn’t work. The stuff the audiol…

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Sunday, March 27, 2016

The neural correlates of cognitive dysfunction in phantom sounds.

In conclusion, these results support for the first time the notion that cognitive changes in tinnitus patients are associated with changes in hippocampal activity as well as the anterior cingulate and insula. PMID: 27016059 [PubMed - as supplied by publisher] (Source: Brain Research)

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Wednesday, March 23, 2016

Chronic Cervicogenic Tinnitus Rapidly Resolved by Intermittent Use of Cervical Collar

Karl Bechter, Martin Wieland, Gerhard F. Hamann (Source: Frontiers in Psychiatry)

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Validation of PRISM (Pictorial Representation of Illness and Self Measure) as a novel visual assessment tool for the burden of suffering in tinnitus patients

Chronic subjective tinnitus is a frequent condition that affects the subject’s quality of life. The lack of objective measures of tinnitus necessitates the use of self-reporting and often time-consuming questi… (Source: Health and Quality of Life Outcomes)

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Endovascular Interventions for Idiopathic Intracranial Hypertension and Venous Tinnitus

Publication date: Available online 22 March 2016 Source:Neuroimaging Clinics of North America Author(s): Ferdinand K. Hui, Todd Abruzzo, Sameer A. AnsariTeaser Pulsatile tinnitus from intracranial venous abnormalities is an uncommon cause of pulse synchronous tinnitus. Endovascular therapies may have applications in many of these disease conditions. They have the advantage of being minimally invasive and may selectively eliminate the site of turbulence. Venous stenting has been used successfully to treat venous stenoses with low complication rates and high success rates in patients with idiopathic intracranial hypertension though randomized controlled data are lacking. Careful exclusion of other causes of tinnitus should be performed before consideration for surgical or endovascular t…

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Tinnitus

Publication date: Available online 22 March 2016 Source:Neuroimaging Clinics of North America Author(s): Suresh K. Mukherji (Source: Neuroimaging Clinics of North America)

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Endovascular Interventions for Idiopathic Intracranial Hypertension and Venous Tinnitus

Pulsatile tinnitus from intracranial venous abnormalities is an uncommon cause of pulse synchronous tinnitus. Endovascular therapies may have applications in many of these disease conditions. They have the advantage of being minimally invasive and may selectively eliminate the site of turbulence. Venous stenting has been used successfully to treat venous stenoses with low complication rates and high success rates in patients with idiopathic intracranial hypertension though randomized controlled data are lacking. Careful exclusion of other causes of tinnitus should be performed before consideration for surgical or endovascular treatment of presumed causative lesions of venous tinnitus. (Source: Neuroimaging Clinics)

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Tinnitus

has been a challenging topic for centuries. When I was “growing up,” we classified tinnitus as “subjective” versus “objective,” “pulsatile” versus “continuous,” or whether there was a retrotympanic mass. The answer to these questions directly affected the imaging evaluation and differential diagnosis. However, the various classifications created much confusion about this topic and led to inconsistent management and treatment of this important disorder. (Source: Neuroimaging Clinics)

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Neuroscience of Tinnitus

Tinnitus is a consequence of changes in auditory and nonauditory neural networks following damage to the cochlea. Homeostatic compensatory mechanisms occur after hearing loss and these mechanisms alter the balance of excitatory and inhibitory neurotransmitters. In many individuals with hearing loss, chronic tinnitus and related phenomena emerge. Some people with tinnitus are disturbed by this subjective sensation. When auditory network dysfunction is coupled with limbic-gating dysfunction, an otherwise meaningless auditory percept such as tinnitus may acquire negative emotional features. The development of effective treatment options is enhanced by the understanding of the neural networks underpinning tinnitus. (Source: Neuroimaging Clinics)

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Tuesday, March 22, 2016

Safety and Efficacy of Gamma Knife Radiosurgery for the Management of Koos Grade 4 Vestibular Schwannomas

CONCLUSION: Patients with Koos grade 4 vestibular schwannomas and minimal symptoms can be treated safely and effectively with GKRS. ABBREVIATIONS: GKRS, Gamma Knife radiosurgery VS, vestibular schwannoma (Source: Neurosurgery)

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Sunday, March 20, 2016

Klinische Aspekte der Cochleaimplantation bei Morbus Menière sowie nach Labyrinthektomie

Laryngo-Rhino-OtolDOI: 10.1055/s-0042-100283 Hintergrund: Aufgrund der natürlichen Alterung und den gelockerten CI-Implantationskriterien werden vermehrt auch früher operierte Menière-Patienten mit einem Cochleaimplantat versorgt werden. Dabei stellt sich jedoch die Frage, ob eine Implantation bei vorbehandeltem Ohr erfolgsversprechend ist. Material und Methode: Anhand von 2 Fällen, bei denen wir eine Cochleaimplantation durchgeführt haben, einerseits 10 Jahre nach transmastoidaler Labyrinthektomie und andererseits bei beidseitigem Morbus Menière, sowie anhand der Literatur weisen wir auf Probleme und Erfolgsaussichten hin. Diskussion: Histologische Studien zeigen nur eine geringe Ossifikation der Cochlea nach Labyrinthektomie. Implantierte Menière-Patienten weisen eine bessere Spra…

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Saturday, March 19, 2016

Relapsing polychondritis and lymphocytic meningitis with varied neurological symptoms

Conclusion Relapsing polychondritis is a challenging disease that can rarely manifest with varied neurological symptoms; recognition is extremely important, because high-dose corticosteroids should be used as soon as possible in suspected cases. (Source: Revista Brasileira de Reumatologia)

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Friday, March 18, 2016

What Is That Noise!?! My Take On Living With Tinnitus

Do you hear that? I often ask my family that question. Sometimes I can’t tell if the noise I am hearing is my tinnitus or if the sound is actually there. Usually, it is all in my head. Typically, I know this, to be honest, but I ask anyway, just in case. I have a 40-50% hearing loss in both of my ears, but only mild tinnitus. I am grateful for that. Sometimes I feel that the tinnitus is worse than the hearing loss! Unexplained sounds buzzing and whistling in your head can make you question your sanity. And give you the worst headache known to man. The lack of sound seems almost a relief in retrospect. Thus far, I have experienced two types of tinnitus. The first has been occurring on and off for several years and is not that troublesome. I am not sure what the trigger is, or even if there …

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Clinical trial on tonal tinnitus with tailor-made notched music training

Tinnitus is a result of hyper-activity/hyper-synchrony of auditory neurons coding the tinnitus frequency, which has developed due to synchronous mass activity owing to the lack of inhibition. We assume that re… (Source: BMC Neurology)

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Tuesday, March 15, 2016

Highway to Hearing Hell: Musicians and the Danger of Deafness

This article was originally published on The Conversation. Read the original article. – This feed and its contents are the property of The Huffington Post, and use is subject to our terms. It may be used for personal consumption, but may not be distributed on a website. (Source: Science - The Huffington Post)

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Sunday, March 13, 2016

Disrupted Functional Brain Connectome in Unilateral Sudden Sensorineural Hearing Loss.

Authors: Xu H, Fan W, Zhao X, Li J, Zhang W, Lei P, Liu Y, Wang H, Cheng H, Shi H Abstract Sudden sensorineural hearing loss (SSNHL) is generally defined as sensorineural hearing loss of 30 dB or greater over at least three contiguous audiometric frequencies and within a three-day period. This hearing loss is usually unilateral and can be associated with tinnitus and vertigo. The pathogenesis of unilateral sudden sensorineural hearing loss is still unknown, and the alterations in the functional connectivity are suspected to involve one possible pathogenesis. Despite scarce findings with respect to alterations in brain functional networks in unilateral sudden sensorineural hearing loss, the alterations of the whole brain functional connectome and whether these alterations were alrea…

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Effects of pulsatile electrical stimulation of the round window on central hyperactivity after cochlear trauma in guinea pig.

This study aimed to investigate the effects of electrical stimulation in the form of brief biphasic shocks delivered to the round window of the cochlea on the spontaneous firing rates of hyperactive inferior colliculus neurons following acoustic trauma in guinea pigs. Effects during the stimulation itself included both inhibition and excitation but spontaneous firing was suppressed for up to hundreds of ms after the cessation of the shock train in all sampled hyperactive neurons. Pharmacological block of olivocochlear efferent action on outer hair cells did not eliminate the prolonged suppression observed in inferior colliculus neurons, and it is therefore likely that activation of the afferent pathways is responsible for the central effects observed. PMID: 26970475 [PubMed - as suppli…

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Hearing Health in College Instrumental Musicians and Prevention of Hearing Loss.

CONCLUSION: Improving the type of information disseminated to college musicians may reduce the risk of ear-related deficits. Noise dosage information, HPD information, and prevention education grounded in theories like the Health Belief Model may increase awareness and promote greater use of HPDs in this population. PMID: 26966962 [PubMed - as supplied by publisher] (Source: Medical Problems of Performing Artists)

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Friday, March 11, 2016

Quality of life and aspects of hearing of collective urban transport workers

Conclusion: the workers of public transport in the present study showed a good level of quality of life, considerable knowledge and limited complaints with regard to hearing issues, tinnitus and dizziness. (Source: Revista CEFAC)

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Surgical Treatment of Tinnitus

This article will address both tinnitus-specific and tinnitus non-specific procedures for objective and subjective causes. (Source: Neuroimaging Clinics)

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Study about the consequences of different sound pressure levels emitted by magnetic resonance imaging equipment

Conclusion: the use of hearing protectors is relevant as a preventive measure for controlling the level of noise that affects the individual’s cochlea, thus minimizing the physical and psycho-social effects resulting from noise exposure. (Source: Revista CEFAC)

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Otoneurological screening of civil construction workers performing work at height

Conclusion: one third of the construction workers who perform work at height presented otoneurological screening results that indicate alteration. (Source: Revista CEFAC)

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Tinnitus: Is there a place for brain stimulation?

Authors: van Zwieten G, Smit JV, Jahanshahi A, Temel Y, Stokroos RJ Abstract Tinnitus is the perception of a “phantom sound” and has a high prevalence. Although many therapies have been investigated within the last decades, there is still no effective standard therapy. Animal studies and human functional imaging studies revealed that tinnitus perception is associated with many complex changes in multiple brain structures. There is growing evidence that brain stimulation might be able to interrupt the local altered neuronal activity and hereby inhibit tinnitus perception. In this editorial review, an update is given on the most promising targets for brain stimulation. Promising structures for stimulation are the dorsal cochlear nucleus, the inferior colliculus and the medial genicul…

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Wednesday, March 9, 2016

Clinical Association Between Brain MRI Findings With Epidural Blood Patch in Spontaneous Intracranial Hypotension

Conclusions: The results of our study indicated no difference between MRI findings in both conservative treatment and EBP modalities; however, there were differences in initial pain score. Therefore, clinical presentation of SIH patients may be critical and help physicians make a decision of EBP procedure. (Source: Journal of Neurosurgical Anesthesiology)

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Tuesday, March 8, 2016

Atypical Feeding and Drainage of Dural AV Fistula

Dural arteriovenous fistulas (DAVF) are frequent causes of pulsatile tinnitus. Color Doppler sonography may play a useful, complementary role to CTA/MRA and digital subtraction angiography (DSA) in the assessment of these anomalies’ characteristics, such as an ipsilateral increased flow volume and a low resistive index. In this article, we report a case of DAVF first detected with Color Doppler sonography that displayed an uncharacteristic venous drainage pattern. Published on 2016-03-07 13:37:35 (Source: Journal of the Belgian Society of Radiology)

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Little research into benefits of wearing earplugs to concerts

Reuters Health - A review of the literature turned up only two high quality studies that looked at whether wearing earplugs to music venues will prevent hearing loss and tinnitus directly afterward. (Source: Reuters: Health)

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Monday, March 7, 2016

Venous Abnormalities Leading to Tinnitus

Venous anomalies are the most commonly identified abnormality by imaging in the work-up for pulse synchronous tinnitus. Potential diagnoses include idiopathic intracranial hypertension, sigmoid sinus wall anomalies, transverse and sigmoid sinus stenosis, jugular bulb anomalies, and prominent posterior fossa emissary veins. These causes are discussed in detail along with the association between sigmoid sinus wall anomalies and idiopathic intracranial hypertension. (Source: Neuroimaging Clinics)

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Advanced Neuroimaging of Tinnitus

Publication date: Available online 5 March 2016 Source:Neuroimaging Clinics of North America Author(s): Prashant Raghavan, Andrew Steven, Tanya Rath, Dheeraj GandhiTeaser Although tinnitus may originate in damage to the peripheral auditory apparatus, its perception and distressing symptomatology are consequences of alterations to auditory, sensory, and limbic neural networks. This has been described in several studies, some using advanced structural MR imaging techniques such as diffusion tensor imaging. An understanding of these complex changes could enable development of targeted treatment. New MR imaging techniques enabling detailed depiction of the labyrinth may be useful when diagnosis of Meniere disease is equivocal. Advances in computed tomography and MR imaging have enabled n…

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Venous Abnormalities Leading to Tinnitus

Publication date: Available online 5 March 2016 Source:Neuroimaging Clinics of North America Author(s): Michael A. Reardon, Prashant RaghavanTeaser Venous anomalies are the most commonly identified abnormality by imaging in the work-up for pulse synchronous tinnitus. Potential diagnoses include idiopathic intracranial hypertension, sigmoid sinus wall anomalies, transverse and sigmoid sinus stenosis, jugular bulb anomalies, and prominent posterior fossa emissary veins. These causes are discussed in detail along with the association between sigmoid sinus wall anomalies and idiopathic intracranial hypertension. (Source: Neuroimaging Clinics of North America)

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Advanced Neuroimaging of Tinnitus

Although tinnitus may originate in damage to the peripheral auditory apparatus, its perception and distressing symptomatology are consequences of alterations to auditory, sensory, and limbic neural networks. This has been described in several studies, some using advanced structural MR imaging techniques such as diffusion tensor imaging. An understanding of these complex changes could enable development of targeted treatment. New MR imaging techniques enabling detailed depiction of the labyrinth may be useful when diagnosis of Meniere disease is equivocal. Advances in computed tomography and MR imaging have enabled noninvasive diagnosis of dural arteriovenous fistulae. (Source: Neuroimaging Clinics)

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Insomnia in patients with chronic tinnitus: Cognitive and emotional distress as moderator variables

Tinnitus is often associated with disturbed sleep, but there are also patients without sleep problems. The mechanisms for developing insomnia or not in tinnitus patients are still unknown. The aim of the present study was to extract possible tinnitus specific factors that increase the risk of developing insomnia based on the analysis of a large patient cohort suffering from chronic tinnitus. (Source: Journal of Psychosomatic Research)

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Saturday, March 5, 2016

but not fetal hemoglobin differentiates chronic mountain sickness from healthy Andean highlanders

Chronic mountain sickness (CMS) results from chronic hypoxia. It is unclear why certain highlanders develop CMS. We hypothesized modest increases in fetal hemoglobin (HbF) is associated with lower CMS severity. In this cross-sectional study, we showed that normal HbF levels (median 0.4%) were found in all 153 adult Andean natives in Cerro de Pasco, Peru. Compared to healthy adults, the borderline elevated hemoglobin group frequently had symptoms (headaches, tinnitus, cyanosis, dilatation of veins) of CMS. (Source: Experimental Hematology)

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Association of tinnitus and hearing loss in otological disorders: a decade-long epidemiological study in a South Indian population

Conclusion The present study could identify the most prevalent otological risk factors leading to development of tinnitus with hearing loss in a South Indian population. (Source: Brazilian Journal of Otorhinolaryngology)

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Thursday, March 3, 2016

Resolution of Concussion Symptoms After Osteopathic Manipulative Treatment: A Case Report.

Authors: Guernsey DT, Leder A, Yao S Abstract A concussion is the result of a biomechanical force directed toward the head, causing neurologic dysfunction. The inflammatory response and the production of reactive oxygen species are proposed mechanisms for the symptoms and long-term sequelae of concussion. Osteopathic manipulative treatment (OMT) may help reduce inflammation by improving glymphatic flow. The authors describe the effect of OMT on a patient with mild concussion symptoms, including nausea, dizziness, tinnitus, and imbalance. The patient was evaluated with the Sensory Organization Test before and after undergoing a 25-minute session of OMT. After the session, the patient reported resolution of symptoms, and his sensory organization test score improved by 6 points. The r…

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Neurotological Findings at a Health Unit for Adults with Cervicalgia

Conclusion Neurotological complaints were frequent in this population, verifying the importance of these tests in the dysfunctions of the cervical region or the craniocervical junction.[…]Thieme Publicações Ltda Rio de Janeiro, BrazilArticle in Thieme eJournals:Table of contents | Abstract | open access Full text (Source: International Archives of Otorhinolaryngology)

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Imaging Interpretation of Temporal Bone Studies in a Patient with Tinnitus

This article provides a summary of the imaging findings of structural causes of tinnitus. (Source: Neuroimaging Clinics of North America)

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Wednesday, March 2, 2016

Flufenamic acid prevents behavioral manifestations of salicylate-induced tinnitus in the rat.

CONCLUSIONS: We suggest that SSA-induced tinnitus could possibly be prevented by administration of a TRPM2 ion channel antagonist, FFA at 66 mg/kg bw. PMID: 26925138 [PubMed - as supplied by publisher] (Source: Archives of Medical Science)

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Imaging Interpretation of Temporal Bone Studies in a Patient with Tinnitus

This article provides a summary of the imaging findings of structural causes of tinnitus. (Source: Neuroimaging Clinics)

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Elevated Acoustic Startle Responses in Humans: Relationship to Reduced Loudness Discomfort Level, but not Self-Report of Hyperacusis

Abstract Increases in the acoustic startle response (ASR) of animals have been reported following experimental manipulations to induce tinnitus, an auditory disorder defined by phantom perception of sound. The increases in ASR have been proposed to signify the development of hyperacusis, a clinical condition defined by intolerance of normally tolerable sound levels. To test this proposal, the present study compared ASR amplitude to measures of sound-level tolerance (SLT) in humans, the only species in which SLT can be directly assessed. Participants had clinically normal/near-normal hearing thresholds, were free of psychotropic medications, and comprised people with tinnitus and without. ASR was measured as eyeblink-related electromyographic activity in response to a noise pulse p…

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Tuesday, March 1, 2016

Symptom: Right-Sided Tinnitus

No abstract available (Source: The Hearing Journal)

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Arterial Abnormalities Leading to Tinnitus

Publication date: Available online 28 February 2016 Source:Neuroimaging Clinics of North America Author(s): Timothy R. Miller, Yafell Serulle, Dheeraj GandhiTeaser Tinnitus is a common symptom that usually originates in the middle ear. Vascular causes of pulsatile tinnitus are categorized by the location of the source of the noise within the cerebral-cervical vasculature: arterial, arteriovenous, and venous. Arterial stenosis secondary to atherosclerotic disease or dissection, arterial anatomic variants at the skull base, and vascular skull base tumors are some of the more common causes of arterial and arteriovenous pulsatile tinnitus. Noninvasive imaging is indicated to evaluate for possible causes of pulsatile tinnitus, and should be followed by catheter angiography if there is a st…

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Tinnitus prevalence in New Zealand.

CONCLUSION: This is the first nationally representative study of tinnitus prevalence in New Zealand and largest study sample internationally for tinnitus prevalence to date. Tinnitus is a public health problem affecting approximately 207,000 people in the New Zealand population aged ≥14 years. This study has highlighted the importance of sex and age in defining a high-risk tinnitus population, but our knowledge falls short of profiling their ethnic and social-economic characteristics. PMID: 26922445 [PubMed - as supplied by publisher] (Source: New Zealand Medical Journal)

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Arterial Abnormalities Leading to Tinnitus

Tinnitus is a common symptom that usually originates in the middle ear. Vascular causes of pulsatile tinnitus are categorized by the location of the source of the noise within the cerebral-cervical vasculature: arterial, arteriovenous, and venous. Arterial stenosis secondary to atherosclerotic disease or dissection, arterial anatomic variants at the skull base, and vascular skull base tumors are some of the more common causes of arterial and arteriovenous pulsatile tinnitus. Noninvasive imaging is indicated to evaluate for possible causes of pulsatile tinnitus, and should be followed by catheter angiography if there is a strong clinical suspicion for a dural arteriovenous fistula. (Source: Neuroimaging Clinics)

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Clinical Evaluation of Tinnitus

Publication date: Available online 28 February 2016 Source:Neuroimaging Clinics of North America Author(s): Ronna Hertzano, Taylor B. Teplitzky, David J. EisenmanTeaser The clinical evaluation of patients with tinnitus differs based on whether the tinnitus is subjective or objective. Subjective tinnitus is usually associated with a hearing loss, and therefore, the clinical evaluation is focused on an otologic and audiologic evaluation with adjunct imaging/tests as necessary. Objective tinnitus is divided into perception of an abnormal somatosound or abnormal perception of a normal somatosound. The distinction between these categories is usually possible based on a history, physical examination, and audiogram, leading to directed imaging to identify the underlying abnormality. (Source:…

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Dural Arteriovenous Fistulae

This article describes the natural history, clinical presentation, classification, imaging features, and management options of intracranial DAVF. (Source: Neuroimaging Clinics of North America)

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Clinical Evaluation of Tinnitus

The clinical evaluation of patients with tinnitus differs based on whether the tinnitus is subjective or objective. Subjective tinnitus is usually associated with a hearing loss, and therefore, the clinical evaluation is focused on an otologic and audiologic evaluation with adjunct imaging/tests as necessary. Objective tinnitus is divided into perception of an abnormal somatosound or abnormal perception of a normal somatosound. The distinction between these categories is usually possible based on a history, physical examination, and audiogram, leading to directed imaging to identify the underlying abnormality. (Source: Neuroimaging Clinics)

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Dural Arteriovenous Fistulae

This article describes the natural history, clinical presentation, classification, imaging features, and management options of intracranial DAVF. (Source: Neuroimaging Clinics)

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Monday, February 29, 2016

Tinnitus prevalence in New Zealand.

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Sunday, February 28, 2016

Dural Arteriovenous Fistulae

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Arterial Abnormalities Leading to Tinnitus

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Arterial Abnormalities Leading to Tinnitus

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Clinical Evaluation of Tinnitus

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Clinical Evaluation of Tinnitus

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Dural Arteriovenous Fistulae

This article describes the natural history, clinical presentation, classification, imaging features, and management options of intracranial DAVF. (Source: Neuroimaging Clinics)

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Progression of unilateral moyamoya disease resulted in spontaneous occlusion of ipsilateral cavernous dural arteriovenous fistula: Case report.

Authors: Liu P, Xu Y, Lv X, Ge H, Lv M, Li Y Abstract The pathogenic association between cavernous dural arteriovenous fistula (CDAVF) and moyamoya disease remains unclear. This unusual case is the first report of a progression of unilateral moyamoya disease resulting in the spontaneous occlusion of ipsilateral CDAVF. A 52-year-old woman presented with two-week spontaneous exophthalmos, chemosis and tinnitus, and cerebral angiography showed a right CDAVF coexisting with ipsilateral moyamoya disease. Transvenous approaches through the inferior petrosal sinus and facial vein were attempted but failed. However, a progression of the moyamoya disease and disappearance of the CDAVF were observed on one month follow-up angiogram in accordance with the resolution of clinical symptoms. This…

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Adaptation of the Arabic Version of the Tinnitus Handicap Inventory

Conclusion The Arabic version of the THI is a valid and reliable tool for the assessment of the impact of tinnitus on the quality of life of Arabic-speaking patients with the complaint of chronic tinnitus. (Source: Otolaryngology - Head and Neck Surgery)

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2015 Equilibrium Committee Amendment to the 1995 AAO-HNS Guidelines for the Definition of Menieres Disease

Ménière’s disease is a disorder of the inner ear that causes attacks of vertigo and hearing loss, tinnitus, aural fullness in the involved ear. Over the past 4 decades, the Equilibrium Committee of the AAO-HNS has issued guidelines for diagnostic criteria, with the latest version being published in 1995. These criteria were reviewed in 2015 by the Equilibrium Committee, and revisions were approved at the recent meeting of the committee at the 2015 AAO-HNSF Annual Meeting. The following commentary outlines the amended and approved criteria. (Source: Otolaryngology - Head and Neck Surgery)

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Friday, February 26, 2016

Cerebral Processing of Emotionally Loaded Acoustic Signals by Tinnitus Patients

This study supports the hypothesis about the existence of a tinnitus-specific brain network. Such a network could respond to any acoustic stimuli by activating limbic areas involved in stress reactivity and emotional processing and by reducing activation of areas responsible for attention and acoustic filtering (thalamus, frontal regions), possibly reinforcing negative effects of tinnitus.Audiol Neurotol 2016;21:80-87 (Source: Audiology and Neurotology)

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Wednesday, February 24, 2016

Long-term vestibulocochlear functional outcome following retro-sigmoid approach to resection of vestibular schwannoma

The objective of this study was to evaluate long-term vestibulocochlear functional outcomes of patients operated for unilateral vestibular schwannoma via the retro-sigmoid approach. Patients who underwent vestibular schwannoma resection via retro-sigmoid approach between 2004 and 2008 at our institution, without prior surgical or radio-surgical therapy were considered to be eligible for this study. Preoperative auditory and vestibular symptoms were assessed retrospectively. Postoperative symptoms were prospectively assessed using a standardised questionnaire, pure tone audiometry, video-oculography, and rotary chair testing. Out of a total of 203 patients, 120 were eligible for this study, of whom 64 responded to follow-up requests and could be enrolled. Serviceable hearing was reported i…

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Tuesday, February 23, 2016

Cervicogenic somatosensory tinnitus: an indication for manual therapy plus education? Part 2: A pilot study

The aim of this study was to evaluate the efficacy of Manual Therapy Utrecht (MTU) plus education in patients with cervicogenic somatosensory tinnitus (CeT). (Source: Manual Therapy)

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Sunday, February 21, 2016

Neuronavigated left temporal continuous theta burst stimulation in chronic tinnitus.

CONCLUSIONS: In our study, verum cTBS was not superior to sham which highlights the persistent need for improving non-invasive brain stimulation techniques for the treatment of tinnitus. Future research should focus on the transfer of positive single session effects to daily treatment trials. PMID: 26890094 [PubMed - as supplied by publisher] (Source: Restorative Neurology and Neuroscience)

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Saturday, February 20, 2016

Variants in the KCNE1 or KCNE3 gene and risk of Ménière's disease: A meta-analysis.

CONCLUSIONS: Based on current evidence from published studies, neither of the two variants from KCNE was significantly associated with the risk of MD. Larger studies with mixed ethnicity subjects and stratified by clinical and sub-clinical characteristics are needed to validate our findings. PMID: 26890422 [PubMed - in process] (Source: Journal of Vestibular Research: Equilibrium and Orientation)

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Friday, February 19, 2016

Salicylate-Induced Hearing Loss Trigger Structural Synaptic Modifications in the Ventral Cochlear Nucleus of Rats via Medial Olivocochlear (MOC) Feedback Circuit.

Authors: Fang L, Fu Y, Zhang TY Abstract Lesion-induced cochlear damage can result in synaptic outgrowth in the ventral cochlear nucleus (VCN). Tinnitus may be associated with the synaptic outgrowth and hyperactivity in the VCN. However, it remains unclear how hearing loss triggers structural synaptic modifications in the VCN of rats subjected to salicylate-induced tinnitus. To address this issue, we evaluated tinnitus-like behavior in rats after salicylate treatment and compared the amplitude of the distortion product evoked otoacoustic emission (DPOAE) and auditory brainstem response (ABR) between control and treated rats. Moreover, we observed the changes in the synaptic ultrastructure and in the expression levels of growth-associated protein (GAP-43), brain-derived neurotrophic…

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A Systematic Review and Meta-Analysis on the Association between Hypertension and Tinnitus.

This study suggests that hypertension might be one risk factor of tinnitus, and hypertension prevention and control might be helpful in preventing tinnitus. PMID: 26881064 [PubMed] (Source: International Journal of Hypertension)

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Thursday, February 18, 2016

A Critical Approach to Evaluating Clinical Efficacy, Adverse Events and Drug Interactions of Herbal Remedies

Systematic reviews and meta‐analyses represent the uppermost ladders in the hierarchy of evidence. Systematic reviews/meta‐analyses suggest preliminary or satisfactory clinical evidence for agnus castus (Vitex agnus castus) for premenstrual complaints, flaxseed (Linum usitatissimum) for hypertension, feverfew (Tanacetum partenium) for migraine prevention, ginger (Zingiber officinalis) for pregnancy‐induced nausea, ginseng (Panax ginseng) for improving fasting glucose levels as well as phytoestrogens and St John’s wort (Hypericum perforatum) for the relief of some symptoms in menopause. However, firm conclusions of efficacy cannot be generally drawn. On the other hand, inconclusive evidence of efficacy or contradictory results have been reported for Aloe vera in the treatment of psori…

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Neural Hyperactivity of the Central Auditory System in Response to Peripheral Damage.

Authors: Zhao Y, Song Q, Li X, Li C Abstract It is increasingly appreciated that cochlear pathology is accompanied by adaptive responses in the central auditory system. The cause of cochlear pathology varies widely, and it seems that few commonalities can be drawn. In fact, despite intricate internal neuroplasticity and diverse external symptoms, several classical injury models provide a feasible path to locate responses to different peripheral cochlear lesions. In these cases, hair cell damage may lead to considerable hyperactivity in the central auditory pathways, mediated by a reduction in inhibition, which may underlie some clinical symptoms associated with hearing loss, such as tinnitus. Homeostatic plasticity, the most discussed and acknowledged mechanism in recent years, is …

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Can YOU hear THIS hissing noise? Tinnitus...and how to live with it

THE sound of silence is something people with tinnitus would treasure - do you know what suffering with the condition is really like? (Source: Daily Express - Health)

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Pulsatile tinnitus and a temporal bone mass

Publication date: Available online 16 February 2016 Source:European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): D.T. Ginat, M.B. Gluth (Source: European Annals of Otorhinolaryngology, Head and Neck Diseases)

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Tuesday, February 16, 2016

Clinical Reasoning: A 37-year-old man with multiple cranial neuropathies

A 37-year-old man presented with a 7-month history of vertigo, nausea, dysphagia, right-sided tinnitus, and hearing loss. He denied headache, paresthesias, change in vision, or problems with cognition. He endorsed a history of progressive fatigue, generalized weakness, and poor libido. His symptoms left him functionally impaired and bedridden. (Source: Neurology)

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Can YOU hear THIS hissing noise? It might mean a trip to the doctor…

THE sound of silence is something people with tinnitus would treasure - do you know what suffering with the condition is really like? (Source: Daily Express - Health)

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The Influence of Tinnitus on the Audiometric Threshold of Sufferers

Conclusion A proportion of tinnitus sufferers with self-professed normal hearing are likely to have mildly elevated pure tone audiometric thresholds. In patients with unilateral tinnitus, such elevated pure tone hearing thresholds are likely to be in the tinnitus ear and the contralateral non-tinnitus ear.[…]Thieme Publicações Ltda Rio de Janeiro, BrazilArticle in Thieme eJournals:Table of contents | Abstract | open access Full text (Source: International Archives of Otorhinolaryngology)

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Endovascular treatment of jugular bulb diverticula causing debilitating pulsatile tinnitus

We describe the case of a patient who presented with debilitating pulsatile tinnitus in association with two jugular bulb diverticula. The diverticula were treated with stenting of the jugular bulb and coil embolization of the diverticula over two procedures. This resulted in successful resolution of symptoms and at 10 months follow-up the patient is asymptomatic. The technique is discussed with regard to similar published cases and surrogate measures of safety taken from the literature pertaining to idiopathic intracranial hypertension. (Source: Journal of NeuroInterventional Surgery)

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Sunday, February 14, 2016

PodMed: A Medical News Roundup From Johns Hopkins (with audio)

(MedPage Today) – This week’s topics include seafood consumption and Alzheimer’s disease, transcranial stimulation for tinnitus, long-term use of marijuana and cognition, and mobile texts for medication adherence (Source: MedPage Today Psychiatry)

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Clinical features of vestibular migraine in Egypt

Conclusions Vestibular migraine is one of the leading causes of dizziness in both adults and children. A high percentage of patients showed abnormalities in Videonystagmography during testing documenting vestibular system involvement in migraine patients during the dizziness attack. Good history taking and analysis of aural symptoms helps in the differential diagnosis. The profile of VM patients is outlined. (Source: Egyptian Journal of Ear, Nose, Throat and Allied Sciences)

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Manual Therapy and Exercise for a Patient With Neck-Tongue Syndrome: A Case Report.

Discussion This case report describes the physical therapy management of an individual with NTS. The management strategy followed a protocol similar to that used for cervicogenic headaches (CH) due to the involvement of the upper cervical spine with both NTS and CH and the lack of evidence for the treatment of NTS. Level of Evidence Therapy, level 4. J Orthop Sports Phys Ther, Epub 11 Jan 2016. doi:10.2519/jospt.2016.6195. PMID: 26868897 [PubMed - as supplied by publisher] (Source: Physical Therapy)

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Saturday, February 13, 2016

Clinical outcomes of middle fossa craniotomy for superior semicircular canal dehiscence repair.

CONCLUSIONS SSCD remains an underdiagnosed and undertreated condition. Surgical repair of SSCD using a middle fossa craniotomy is associated with a high rate of symptom resolution. Continued investigation using a larger patient cohort and longer-term follow-up could further demonstrate the effectiveness of using middle fossa craniotomy for SSCD repair. PMID: 26871374 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)

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Friday, February 12, 2016

Prevalence of Pulsatile Tinnitus Among Patients With Migraine

Conclusion: PT can be observed in the context of migraine. Migraine treatment with avoidance of dietary triggers with or without medication can possibly lead to resolution of PT. (Source: Otology and Neurotology)

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Notched environmental sounds: a new hearing aid‐supported tinnitus treatment evaluated in 20 patients

(Source: Clinical Otolaryngology)

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Can YOU hear this hissing, buzzing, ROARING noise? It might mean a trip to the doctor…

THE sound of silence is something people with tinnitus would treasure - do you know what suffering with the condition is really like? (Source: Daily Express - Health)

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Prospective case‐controlled sound localisation study after cochlear implantation in adults with single‐sided deafness and ipsilateral tinnitus

ConclusionsSubjects can better locate sound in the CION condition than in the CIOFF condition. (Source: Clinical Otolaryngology)

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Wednesday, February 10, 2016

Acupuncture as a Treatment Option in Treating Posttraumatic Stress Disorder-Related Tinnitus in War Veterans: A Case Presentation

This article presents a case of three war veterans with PTSD symptoms who received a series of acupuncture treatments for tinnitus with positive outcomes. Even though the article presents cases of only three veterans and was based on self-reports, there were very clear trends on how veterans with tinnitus symptoms responded to acupuncture treatments. Information generated from this case presentation is a good starting place in exploring evidence-based approaches in treating tinnitus symptoms in war veterans with PTSD. (Source: Journal of Holistic Nursing)

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Monday, February 8, 2016

Deafferentation-based pathophysiological differences in phantom sound: Tinnitus with and without hearing loss

Publication date: 1 April 2016 Source:NeuroImage, Volume 129 Author(s): Sven Vanneste, Dirk De Ridder Tinnitus has been considered an auditory phantom percept. Recently a theoretical multiphase compensation mechanism at a cortical level has been hypothesized linking auditory deafferentation to tinnitus. This Bayesian brain model predicts that two very different kinds of tinnitus should exist, depending on the amount of hearing loss: an auditory cortex related form of tinnitus not associated with hearing loss, and a (para)hippocampal form associated with hearing loss, in which the auditory cortex might be of little relevance. In order to verify this model, resting state source analyzed EEG recordings were made in 129 tinnitus patients, and correlated to the mean hearing loss, the range …

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Effects of Erlong Zuoci decoction on the age-related hearing loss in C57BL/6J mice

Conclusion The results demonstrated that ELZCD prevented ARHL in C57BL/6J mice and p53/Bak-mediated mitochondrial apoptosis of SG cells might be involved in the mechanisms. Graphical abstract (Source: Journal of Ethnopharmacology)

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Sunday, February 7, 2016

Separation of Power-line Noise from Tinnitus Sound, to aid medical diagnoses

Publication date: Available online 6 February 2016 Source:Perspectives in Science Author(s): J. Dhoulath Beegum, D. Chithraprasad, Alan Jacob, D.S. Ananthakrishnan, Gayatri Nair, Namitha S. Nair, Irene Miriam Isaac Tinnitus, is one of the leading symptom in neurological disorders, particularly relating with diseases of the middle ear, blood vessels or the aftereffect as a result of exposure to certain medications. The preliminary diagnosis of tinnitus is established by subjecting the patient to common tinnitus simulated sounds. This helps to assess the patient’s perception of tinnitus on a score that helps in planning further treatments involved with medications or advanced interventions. The major drawback within this widely accepted preliminary diagnosis technique is that of the…

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Friday, February 5, 2016

Emerging hubs in phantom perception connectomics

Publication date: Available online 4 February 2016 Source:NeuroImage: Clinical Author(s): Anusha Mohan, Dirk De Ridder, Sven Vanneste Brain networks are small-world networks typically characterized by the presence of hubs, i.e. nodes that have significantly greater number of links in comparison to other nodes in the network. These hubs act as short cuts in the network and promote long-distance connectivity. Long-distance connections increase the efficiency of information transfer but also increase the cost of the network. Brain disorders are associated with an altered brain connectome which reflects either as a complete change in the network topology, as in, the replacement of hubs or as an alteration in the connectivity between the hubs while retaining network structure. The current …

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Relationship between tinnitus and suicidal behaviour in Korean men and women: a cross‐sectional study

ConclusionThis study has important implications for enhanced screening and evaluation of mental health status and suicidal ideation/behaviour among tinnitus patients. (Source: Clinical Otolaryngology)

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Could the biological robustness of low level laser therapy (Photobiomodulation) impact its use in the management of mucositis in head and neck cancer patients

Low level laser therapy (LLLT) was first introduced for potential clinical applications by Mester in the late 1960s. This form of laser treatment, currently referred to as photobiomodulation (PBM), limits radiation intensity by transferring low energy to tissues and thereby does not generate heat. Among the clinical indications for which LLLT has been reported to be efficacious are pain relief (back and neck, orthodontic, shoulder), wound healing, carpal tunnel syndrome, colorectal cancer, elbow disorders, fibromyalgia, lymphedema, musculoskeletal dysfunction, myofascial pain syndrome, neurological dysfunctions, patella-femoral pain syndrome, rheumatoid arthritis, shoulder impingement syndrome, and tinnitus. (Source: Oral Oncology)

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New scoring system of an interview for the diagnosis of benign paroxysmal positional vertigo.

Conclusion This study investigated a novel instrument to diagnose benign paroxysmal positional vertigo (BPPV). Objective To develop a new scoring system of an interview for the diagnosis of BPPV. Methods The answers to questions on dizziness and/or vertigo (D/V) (571 patients) were analyzed and the questions for which the answers differed significantly between the patients with and without BPPV were selected. Results This study established an intensive questionnaire with a scoring system. It consists of the following questions: (1) Is rotary vertigo a characteristic of your D/V? (2) Is your D/V triggered when you roll your head over in a supine position? (3) Does your D/V disappear within 5 min? (4) Have you previously experienced hearing loss in one ear, or have you experienced hearing lo…

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Thursday, February 4, 2016

Relieve ringing ears with these eight natural remedies

(NaturalNews) Ringing in the ears – or tinnitus – is one of the most annoying conditions you can develop. It can have a big impact on your ability to hear, as well as being incredibly distracting and interfering with your daily life.(1)Tinnitus is quite… (Source: NaturalNews.com)

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Wednesday, February 3, 2016

Transcranial Magnetic Stimulation for Chronic Tinnitus

This commentary discusses a study published in JAMA Otolaryngology–Head & Neck Surgery that evaluated transcranial magnetic stimulation for the treatment of chronic tinnitus. (Source: JAMA)

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A mutation of the succinate dehydrogenase B gene in a Korean family with paraganglioma

We report a case of germline SDHB mutation. This mutation was a deletion of thymine at nucleotide position 757 in exon 7 of the SDHB gene (c.757delT). (Source: Familial Cancer)

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AMA Hearing Loss/Tinnitus Guidelines

No abstract available (Source: The Hearing Journal)

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The relationship between tinnitus and vascular anomalies on temporal bone CT scan: a retrospective case control study

Conclusions In patients who complained of subjective nonpulsatile tinnitus with unknown etiology, some temporal bone vascular variations, including high riding jugular bulb, dehiscent carotid canal, left-sided MEV enlargement, and petrous bone pneumatization, seemed to have an association with tinnitus. Further studies comparing all these entities between pulsatile and nonpulsatile groups and healthy controls should be undertaken. (Source: Surgical and Radiologic Anatomy)

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Tuesday, February 2, 2016

Pitch and Loudness Tinnitus in Individuals with Presbycusis

Conclusion There is no significant association between the hearing loss of patients with presbycusis and the pitch and loudness of tinnitus.[…]Thieme Publicações Ltda Rio de Janeiro, BrazilArticle in Thieme eJournals:Table of contents | Abstract | open access Full text (Source: International Archives of Otorhinolaryngology)

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Friday, January 29, 2016

Spatial Masking: Development and Testing of a New Tinnitus Assistive Technology.

CONCLUSIONS: This study indicates that spatial masking of tinnitus is feasible, of benefit to many participants, and warrants further trials. PMID: 26817495 [PubMed - as supplied by publisher] (Source: Assistive Technology)

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Which tinnitus-related characteristics affect current health-related quality of life and depression? A cross-sectional cohort study

Tinnitus is sometimes associated with lower health-related quality of life (HRQoL) and depressive symptoms. However, only limited evidence exists identifying which tinnitus characteristics are responsible for these associations. The aim of this cross-sectional study was to assess associations between tinnitus, HRQoL, depressive symptoms, subjective tinnitus loudness and audiometrically assessed tinnitus characteristics (e.g., hearing threshold). Two hundred and eight outpatients reporting tinnitus completed questionnaires on tinnitus (Tinnitus Handicap Inventory, THI), HRQoL (World-Health-Organisation Quality of Life Short Form Survey, WHOQOL-BREF), and depressive symptoms (Beck Depression Inventory, BDI), and underwent audiometry. (Source: Psychiatry Research)

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Long‐Term Distributed Repetitive Transcranial Magnetic Stimulation for Tinnitus: A Feasibility Study

ConclusionsOur study demonstrated that rTMS can be delivered in a distributed schedule that is well‐tolerated, feasible and may prove to be clinically beneficial. A long‐term distributed rTMS schedule for tinnitus may warrant investigation as an alternative to the short‐term aggregated treatment schedules more frequently used previously. For the many varied therapeutic uses of rTMS (established and investigational), treatment schedules are relatively unexplored, and deserve further attention. (Source: Neuromodulation: Technology at the Neural Interface)

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Thursday, January 28, 2016

Hearing difficulty and tinnitus among U.S. workers and non‐workers in 2007

ConclusionsHearing difficulty and tinnitus are prevalent in the U.S.; especially among noise‐exposed workers. Improved strategies for hearing conservation or better implementation are needed. Am. J. Ind. Med. Published 2016. This article is a U.S. Government work and is in the public domain in the USA (Source: American Journal of Industrial Medicine)

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Protective effects of the seaweed phlorotannin polyphenolic compound dieckol on gentamicin-induced damage in auditory hair cells

This study investigated the protective effects of dieckol on drug-induced ototoxicity in cochlear cultures obtained from neonatal mice. (Source: International Journal of Pediatric Otorhinolaryngology)

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Monday, January 25, 2016

Altered top-down cognitive control and auditory processing in tinnitus: evidences from auditory and visual spatial stroop.

CONCLUSIONS: Tinnitus is associated both with modality-specific deficits along the auditory processing system and an impairment of cognitive control mechanisms that are involved both in vision and audition (i.e. that are supra-modal). We postulate that this deficit in the top-down cognitive control is a key-factor in the development and maintenance of tinnitus and may also explain some of the cognitive difficulties reported by tinnitus sufferers. PMID: 25420904 [PubMed - indexed for MEDLINE] (Source: Restorative Neurology and Neuroscience)

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Diagnostic criteria for Menière's disease.

Authors: Lopez-Escamez JA, Carey J, Chung WH, Goebel JA, Magnusson M, Mandalà M, Newman-Toker DE, Strupp M, Suzuki M, Trabalzini F, Bisdorff A Abstract This paper presents diagnostic criteria for Menière’s disease jointly formulated by the Classification Committee of the Bárány Society, The Japan Society for Equilibrium Research, the European Academy of Otology and Neurotology (EAONO), the Equilibrium Committee of the American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) and the Korean Balance Society. The classification includes two categories: definite Menière’s disease and probable Menière’s disease. The diagnosis of definite Menière’s disease is based on clinical criteria and requires the observation of an episodic vertigo syndrome associated with low- to me…

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Saturday, January 23, 2016

Attentional Bias in Patients with Decompensated Tinnitus: Prima Facie Evidence from Event-Related Potentials

In this study, we adopted an objective indicator of attentional processing, i.e. the mismatch negativity (MMN), to assess the attentional bias in patients with decompensated tinnitus. Three kinds of pure tones, D1 (8,000 Hz), S (8,500 Hz) and D2 (9,000 Hz), were used to induce event-related potentials (ERPs) in the normal ear. Employing the oddball paradigm, the task was divided into two blocks in which D1 and D2 were set as deviation stimuli, respectively. Only D2 induced a significant MMN in the tinnitus group, while neither D1 nor D2 was able to induce MMN in the control group. In addition, the ERPs in the left hemisphere, which were recorded within the time window of 90-150 ms (ERP90-150 ms), were significantly higher than those in the right hemisphere in the tinnitus group, while no s…

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Friday, January 22, 2016

Hearing complaints of workers in a pottery industry of the city of João Pessoa/PB

Conclusion: the results of this study show a direct association between time of exposure to noise and auditory symptoms, which suggests that better hearing health education politics may be necessary. In addition, it was found that workers knew the risks of noise on health, but did not comprehend that the auditory symptoms they have may be associated with this important physical risk, which can hinder actions to prevent noise hazards. (Source: Revista CEFAC)

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Thursday, January 21, 2016

Ultrasound exposure could be making people ill, study finds

University of Southampton research finds public places can feature high frequency sounds beyond occupational health limitsExposure to high frequency sounds beyond the range of human hearing from public address systems, loudspeakers and door sensors in public places could be making people feel ill, research suggests.Increasing exposure to ultrasound in the air was recorded in railway stations, museums, libraries, schools and sports stadiums in which it is claimed people have complained of nausea, dizziness, migraine, fatigue and tinnitus. Continue reading… (Source: Guardian Unlimited Science)

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Wednesday, January 20, 2016

Surgical management of vestibular schwannomas after failed radiation treatment

Abstract Increasing numbers of patients with vestibular schwannoma (VS) have been treated with focused-beam stereotactic radiation treatment (SRT) including Gamma knife, CyberKnife, X-knife, Novalis, or proton beam therapy. The purpose of this study was to document the incidence of tumor regrowth or symptoms that worsened or first developed following SRT and to discuss surgical strategies for patients who have failed SRT for VS. A consecutive series of 39 patients with SRT failed VS were surgically treated. Clinical symptoms, tumor regrowth at follow-up, intraoperative findings, and surgical outcome were evaluated. There were 15 males and 24 females with a mean age of 51.8 years. Thirty-six patients (92.3 %) demonstrated steady tumor growth after SRT. Two (5.1 %) patients with …

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Genetic risk factors of cisplatin induced ototoxicity in adult patients.

The objective of this prospective study was to investigate a possible genetic background to this variability. We assessed ototoxicity induced by therapeutic doses of CDDP in adult patients with germinative testicular tumors, or other tumors treated with an identical CDDP dosage scheme. Audiological examination before, during and after the treatment has shown deterioration in hearing; first in the high-frequencies and with increased CDDP cumulative doses, impairment in other frequencies as well. Occurrence of tinnitus was not dependent on the administered dose of CDDP, or the other risk factors examined in this study. The association of CDDP induced ototoxicity with genetic polymorphisms in candidate genes was examined. Our study has demonstrated an association of early onset of CDDP induc…

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Saturday, January 16, 2016

Effects of Intralabyrinthine Hemorrhage on the Cochlear Elements: A Human Temporal Bone Study

Conclusion: These findings suggest that such patients could be good candidates for hearing aid or cochlear implant if they have profound sensorineural hearing loss. (Source: Otology and Neurotology)

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Friday, January 15, 2016

Disability evaluation in acoustic blast trauma

Conclusion: Objective hearing tests should be carried out after one year or more before evaluation of permanent disability. (Source: Indian Journal of Occupational and Environmental Medicine)

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Thursday, January 14, 2016

Postoperative Imaging Findings following Sigmoid Sinus Wall Reconstruction for Pulse Synchronous Tinnitus [HEAD & NECK]

CONCLUSIONS: The imaging findings following sigmoid sinus wall repair are characteristic. Graft materials may result in extrinsic compression of the sigmoid sinus, and this finding may be confused with dural venous thrombosis. Awareness of the imaging characteristics of the graft materials used enables this differentiation. (Source: American Journal of Neuroradiology)

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Wednesday, January 13, 2016

Sodium salicylate reduces the level of GABAB receptors in the rat’s inferior colliculus

Publication date: 1 March 2016 Source:Neuroscience, Volume 316 Author(s): S. Butt, F. Ashraf, L.A. Porter, H. Zhang Previous studies have indicated that sodium salicylate (SS) can cause hearing abnormalities through affecting the central auditory system. In order to understand central effects of the drug, we examined how a single intraperitoneal injection of the drug changed the level of subunits of the type-B γ-aminobutyric acid receptor (GABAB receptor) in the rat’s inferior colliculus (IC). Immunohistochemical and western blotting experiments were conducted three hours following a drug injection, as previous studies indicated that a tinnitus-like behavior could be reliably induced in rats within this time period. Results revealed that both subunits of the receptor, GABABR1 and …

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Altered vesicular glutamate transporter distributions in the mouse cochlear nucleus following cochlear insult

Publication date: 19 February 2016 Source:Neuroscience, Volume 315 Author(s): A.N. Heeringa, R.A. Stefanescu, Y. Raphael, S.E. Shore Vesicular glutamate transporters 1 and 2 (VGLUT1 and VGLUT2) have distinct distributions in the cochlear nucleus that correspond to sources of the labeled terminals. VGLUT1 is mainly associated with terminals of auditory nerve fibers, whereas VGLUT2 is mainly associated with glutamatergic terminals deriving from other sources that project to the cochlear nucleus (CN), including somatosensory and vestibular terminals. Previous studies in guinea pig have shown that cochlear damage results in a decrease of VGLUT1-labeled puncta and an increase in VGLUT2-labeled puncta. This indicates cross-modal compensation that is of potential importance in somatic tinni…

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Visual snow: A thalamocortical dysrhythmia of the visual pathway?

Publication date: Available online 11 January 2016 Source:Journal of Clinical Neuroscience Author(s): Jenny L. Lauschke, Gordon T. Plant, Clare L. Fraser In this paper we review the visual snow (VS) characteristics of a case cohort of 32 patients. History of symptoms and associated co-morbidities, ophthalmic examination, previous investigations and the results of intuitive colourimetry were collected and reviewed. VS symptoms follow a stereotypical description and are strongly associated with palinopsia, migraine and tinnitus, but also tremor. The condition is a chronic one and often results in misdiagnosis with psychiatric disorders or malingering. Colour filters, particularly in the yellow-blue colour spectrum, subjectively reduced symptoms of VS. There is neurobiological evidence f…

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Tuesday, January 12, 2016

Malignant Jugular Paraganglioma: Unusual Presentation on 68Ga DOTANOC PET/CT

We report a 40-year-old woman of jugular paraganglioma, presenting with right-sided neck swelling, hearing loss, and pulsatile tinnitus. Contrast-enhanced CT temporal bone revealed a mass in the right jugular foramina and extending inferiorly to internal jugular vein. 68Ga DOTANOC PET/CT was performed, which revealed somatostatin receptor expressing lesion in the right internal jugular vein and extension into sigmoid sinus and additional metastatic focus in the sacrum. (Source: Clinical Nuclear Medicine)

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Tinnitus and its current treatment–Still an enigma in medicine

Publication date: Available online 30 December 2015 Source:Journal of the Formosan Medical Association Author(s): Santosh Kumar Swain, Saumyadarshan Nayak, Jayprakash Russel Ravan, Mahesh Chandra Sahu Tinnitus is a phantom auditory perception that occurs in humans. Tinnitus, which is a distressing problem affecting many people around the world, is commonly referred to as ringing in the ears. No effective drug therapy is available for this elusive disease, although much research work into mechanism and possible treatment is underway. As yet, there are no Food and Drug Administration approved drugs available and the quest for a new treatment option for tinnitus focus on important challenges in tinnitus management. A number of options have been used to treat patients with tinnitus, but …

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Comparison of nerve combing and percutaneous radiofrequency thermocoagulation in the treatment for idiopathic trigeminal neuralgia

Conclusion Nerve combing and RF are both satisfactory treatment strategies for patients with ITN. Because of the higher risk of sensory morbidity and surgical risk as open surgery, RF is preferred as the recommended procedure for patients with ITN. (Source: Brazilian Journal of Otorhinolaryngology)

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Treatment of Meniere’s disease with Intratympanic Dexamethazone plus High Dosage of Betahistine

Conclusions Our preliminary results demonstrate that complete and substantial vertigo control is significantly higher in patients treated with a combination of HDBH and ITD. (Source: American Journal of Otolaryngology)

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Well: Think Like a Doctor: Thunder in the Head

Can you solve a real-life medical mystery involving a 59-year-old man tormented by a thunderous pounding in his head? (Source: NYT)

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Well: Think Like a Doctor: Thunder in the Head Solved

Readers try to solve the case of a middle aged man who developed chest pain that radiated to his neck, followed by a persistent and loud whooshing in his ear. (Source: NYT)

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The effectiveness of acupuncture as a treatment for tinnitus: a randomized controlled trial using 99m Tc-ECD SPECT

Conclusions ACP might reduce the effects of tinnitus on daily life; however, additional studies should be conducted to verify the effects of ACP on the neural architecture and brain function of tinnitus patients. Key Points • Efficacy of acupuncture on brain perfusion and symptoms of tinnitus patients. • Acupuncture improved the Tinnitus Handicap Inventory scores in tinnitus patients. • No significant changes in brain perfusion were observed after 12 twice-weekly sessions. • Perfusion changes would reflect changes in neuronal function. (Source: European Radiology)

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